A new study validate a theory controversial cancer, namely the yeast in our body can help feed not only, but actually causes cancer. Can the ancient healing art of the spice turmeric come to the rescue?
A recent study published in Critical Reviews in Microbiology supports the concept that the opportunistic Candida albicans (yeast) infection can not only be a result of cancer, but it is a cause that also actively contributes.
Under the heading, “ Candida albicans and cancer: Can this yeast induce cancer development or progression “, the study provides the following important information on this controversial subject:
currently there is growing concern about the relationship between microbial infections and cancer. More and more studies support the idea that there is an association, especially when the causative agents are bacteria or viruses. This review adds to this, summarizing evidence that the opportunistic fungus Candida albicans increases the risk of carcinogenesis and metastasis. Until a few years ago Candida spp. It had mainly been linked to cancer processes, as it is an opportunistic pathogen that takes advantage of state of immunosuppression of patients in particular due to chemotherapy. In contrast, recent findings show that C. albicans is able to promote cancer by several mechanisms, such as described in the review: production of carcinogenic byproducts, triggering inflammation, induction of Th17 response and molecular mimicry. We stress the need not only to control this type of infection during cancer treatment, especially considering the important role of this yeast species in nosocomial infections, but also to find new therapeutic approaches to prevent pro-tumor effect of this species of fungi.
The four different ways in which Candida albicans can contribute to cancer are explained in more detail below:
The production of carcinogenic [19459011byproducts]: first, Candida Albicans produce nitrosamines, which are carcinogens that activate proto-oncogenes that could cause specific cancerous lesions. Second, Candida albicans produce acetaldehyde which occurs as the first metabolite of ethanol (the product of yeast fermentation), and which is a chemical which damages DNA (mutagenic) and carcinogenic a wide range of properties promoter cancer, downstream.
Activation of inflammation : prolonged inflammation unresolved can promote cancer, thus causing damage to tissues, and through secretion products proliferative chemicals intended to stimulate regeneration of damaged tissue, but can cause the tissue immortalized when inflammation is chronic and misdirected. Candida albicans is well known to promote a cascade of inflammatory responses in the body to grow beyond its normal population density due to immunosuppression, poor diet, and / or chemical exposure. These inflammatory responses wrong found to promote increases in tumor cell adhesion, which is believed to promote the formation of secondary tumors and / or metastases.
The induction of Th17 answer: The set of CD4 T cells that are dominant in response to Candida albicans, ie, the TH17 cells also secrete factors that can promote angiogenesis (formation of new blood vessels) and increased tumor incidence and growth.
Molecular mimicry: Antibodies raised against a protein on the surface of Candida albicans (CR3-RP) has structural and antigenic similarities to a receiver in some of our white blood cells (leukocytes). This “molecular mimicry” can cause antibodies formed against our immune cells then disrupt anti-tumor and anti-Candida host defenses.
This newly identified research not only confirms the notion that the proliferation of yeast can be a contributing cause cancer, but also, indirectly, raises a red flag that both sugar and alcohol. Clearly, if the sugar and ethanol conversion to produce acetaldehyde, reducing excessive consumption of any chemopreventive is a good step, and is likely to completely necessary intervention when treating cancers actively established -. That is, if the goal is complete remission
Moreover, sugar has also been recently discovered that not only feed the cancer, but actively contributes to the transformation of normal cells into cancer; ie Sugar is potentially carcinogenic . Read my recent article, “ Research Reveals How sugar causes cancer ,” for more information.
The implications of this research are profound since sugar also promotes the growth of yeast, which means that sugar is both directly and indirectly carcinogens; a fact that is even more worrying given rooms cancer treatment in major hospitals continue to give food and drink to their patients while on treatment, or recovering from treatment containing sugar.
A new study published in European Journal of Pharmacology reveals that the main polyphenol in turmeric known as curcumin can be the perfect way to fight cancers that have a component of fungi.
Under the heading, “ Curcumin and its promise as a cancer drug: an analysis of its anti-cancer effects and antifungals cancer and complications of invasive fungal infections , “the new study addressed the relative problem of invasive fungal infections, as one of the leading causes of morbidity and mortality in patients with cancer. According to the study, “An effective therapy against infection is necessary to inhibit significant deterioration of these infections. However, they are difficult to treat, and increased resistance to antifungal drugs often leads to relapse” The authors suggest the curcumin could offer an ideal natural alternative :.
Curcumin, a natural compound that is isolated from the rhizome of Curcuma longa plant, it has attracted great interest among scientists studying many solid cancers over the last half century. Interestingly, curcumin offers an ideal alternative to current therapies due to their relatively safe profile, even at high doses. To date, it has been reported potent antifungal activity of curcumin against different strains of Candida, Cryptococcus, Aspergillus, Trichosporon and Paracoccidioides, indicating that cancer drugs curcumin may also have an antifungal paper, to help cancer patients to resist complications related to invasive fungal infection. The objective of this review is to discuss dual pharmacological activities of curcumin in their applications as a natural anti-cancer and anti-fungal agent. It is expected that these pharmacological activities dual to conduct clinical trials and to improve survival of infection among patients with cancer. “
The study went on to explain that conventional therapies often result in collateral damage to the immune system of the patient, contributing to the growth of fungi. in addition, conventional medicines for fungal infections can cause serious damage to the liver and kidneys of patients, besides leading to the emergence of fungal infections still more aggressive, resistant to therapy.
Moreover, conventional cancer treatments only attack one aspect of cancer, focusing on a single pathway or molecule on a cancer cell. This is why curcumin has much more promising as a “next drug generation multi-purpose.” not only the fight against fungal infections, but has the ability to deal with a multitude of cancer targets, including the possibility of destroy the subpopulation of cancer stem cells , located in root of cancer malignancy and recurrence .
The study concluded:
Curcumin is a drug up-and-coming naturally occurring multi-target properties, and has been displayed against effective cancer alone or in combination with conventional chemotherapy drugs and antifungal agents antifungal activities. Dual pharmacological activities of curcumin can make it a good candidate for the prevention and treatment of cancer and its complications related to invasive fungal infections associated with cancer. more research to clarify the mechanisms of anticancer and antifungal curcumin for a better understanding is needed. Although useful biological activities of curcumin, its poor solubility in water and low bioavailability hampers clinical applications. Various delivery systems nanosized curcumin, such as nanoparticles, nanospheres, lipid nanoparticles solid, micelles, and liposomes have been shown to overcome these drawbacks and significantly improve anticancer and antifungal activities of curcumin. Many studies on curcumin and its nanoformulations are still in the preclinical stage today. A stage of clinical trials is needed to unlock the potential of curcumin nanoformulations as a therapeutic strategy for the treatment of cancer and its complications IFI. “
Indeed, curcumin is rapidly becoming the grass more extensively researched and most promising for prevention and treatment of known disease, with at least 750 potential therapeutic applications studied. for more information visit our database Research turmeric . for more research on natural substances that fight Candida albicans infections visit our database on the subject .
Sayer Ji is the founder of Greenmedinfo.com , where this article first appeared . He is on the Board of Governors of National Health Federation and Parents Without Fear , Member of the Executive Committee of OMG global free Coalition (GGFC) a reviewer in International Journal of human Nutrition and functional Medicine . As in Facebook – Continue on Twitter
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