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Plant compounds could help stop colon cancer spread

Natural Health News – New evidence suggests that components of turmeric and thistle milk may have a protective effect against colon cancer.

Excluding skin cancers, colon cancer (also known as colon or colorectal) is the fourth most common cancer diagnosed in men and women in the UK and the third most common cancer in the US .S ..

previous studies have reported a link between diet and this form of cancer. Similarly, phytochemicals found in fruits, vegetables and spices have been found to have a protective effect.

A new laboratory study published in the Journal of Cancer suggested that the combination of curcumin and silymarin can inhibit the spread of cancer cells Colon and increase cancer cell death.

Curcumin is the active ingredient in turmeric, which is present in hot curry dishes, and silymarin is a component of milk thistle, which has been used to treat liver disease.

What you need to know

A recent laboratory study silymarin and curcumin derived from milk thistle and turmeric, respectively, could stop the growth and spread of cells of colon cancer.

The results showed that the two worked best in combination and that positive results could be seen at very low levels of exposure in the laboratory.

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Researchers treated cell lines with human colon cancer curcumin alone, silymarin alone or a combination of curcumin and silymarin. Then evaluated cell proliferation, the process results in an increase in cell number.

A combination works best

The results showed that silymarin only showed significant inhibition of cell growth, but only at higher concentrations. However, curcumin alone exhibited a marked effect on the inhibition of cell growth in a manner dependent on the concentration, from a very low concentrations.

The researchers found the treatment of the cells initially with curcumin, then with silymarin was more effective in the fight against cancer that treatment of cells with phytochemical alone, said Uthayashanker Ezekiel, Ph .D., corresponding author and associate professor of biomedical science in the laboratory saint Louis University.

“The combination of phytochemicals inhibits cells of colon cancer multiply and spread. Furthermore, when cells of colon cancer were pre-exposed to curcumin and then treated with silymarin, the cells were a high amount of cell death, “Ezekiel said.

“Phytochemicals can offer alternative therapeutic approaches to cancer treatment and avoid problems of toxicity and side effects of chemotherapy can cause.”

Ezekiel noted that while the research is preliminary saw the promise in the use of phytochemicals to help prevent colon cancer, which often is caused by factors of lifestyle, such as diet.

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“We still have much to learn,” Ezekiel said and warned against the “mega-dose” with supplements, suggesting that, “For now, it is much safer to add a little spice to your diet and get your curcumin from foods containing turmeric, like curry, instead of taking high doses of the compound. “

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