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Milk thistle protects against non-alcoholic fatty liver disease

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milk thistle

(NaturalHealth365) disease NAFLD (NASH) is exactly what it sounds like – an accumulation of fat in the liver, along with a history of little or no consumption of alcoholic beverages. NAFLD is common – some experts estimate that its prevalence to 45 percent of the population in industrialized countries of North America and Europe – and can be quite mild, with obvious symptoms. So let’s see how thistle, a natural herb, may help prevent liver damage.

In severe cases, NAFLD is the beginning of a fatal progression that begins with excess fat in the liver, is developed NASH – involving inflammation and hepatic fibrosis – and ultimately it results in this type of life-threatening complications such as liver cirrhosis, liver cancer and liver failure.

Milk thistle, scientifically known as Silybum, much appreciated since by herbalists and naturopaths as a tonic to help chronic liver problems and kidney combat. Now, studies in animals and humans have begun to reveal the extent of the healing powers of milk thistle and its multiple mechanisms of action -. And with the support of its use as a safe and extremely promising treatment for NAFLD and its complications

The metabolic syndrome is a major cause of NAFLD; mechanisms milk thistle seem designed to protect against both conditions.

Metabolic syndrome is the general term for a long list of unhealthy conditions, including abdominal obesity, high blood pressure inadequate control blood sugar and excess fat in the bloodstream. Metabolic syndrome is particularly harmful to the liver -. as a first line of defense against toxins from your system, your liver is the main victim of the effects of harmful substances such as fats, sugars, free radicals and drugs

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In short, milk thistle improves liver function across the board. More specifically, the liver detoxifies, reduces the damage caused by oxidative stress, regulates fat metabolism and helps clean the blood of toxins – thereby suppressing insulin resistance inflammation and obesity They are contributing to both metabolic syndrome and most likely consequence :. NAFLD

Indeed, in an animal study, silybin – a flavonoid found in milk thistle -. Was found to be more effective than Avandia diabetes drug pharmaceutical stabilize the metabolism of energy management of liver cells
extracts of milk thistle are able to change the structure of liver cells in order to boost cellular defense mechanisms -. including increasing the number and function of mitochondria in liver cells

It is because of this property that changes the cell that many researchers are proving milk thistle with the ability of preventing liver fibrosis and subsequent progression to cirrhosis.

I see references to both the silybin and silymarin as extracts of milk thistle, and the terms seem to be used interchangeably. Naturally, many people wonder ‘Are they the same substance?’

Although the silybin and silymarin are sometimes used as if they are synonymous, that are not exactly the same . Silybin, which constitutes about 50 to 70 percent silymarin extract, is one of the seven components that make silymarin. An extremely powerful antioxidant, silybin is considered the most active ingredient silymarin.

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In a clinical study published in 2013 World Journal of Hepatology , the research team concluded that the silybin is effective in reducing biochemical, inflammatory and ultrasonic indices fatty liver.

In a 2014 study published in eight weeks Caspian Journal of Internal Medicine , patients with NASH were divided into two groups. All participants received recommendations lifestyle changes of diet and exercise, but only one group was given the silybin, at the dose of 210 mg per day. The group had the silybin significantly greater reductions in total serum enzymes than a control group that did not receive the extract.

The researchers acknowledged that the silybin is a herbal treatment “useful” and noted its safety and lack of side effects.

What is the best way to use extracts of milk thistle?

Look no GMO, non-irradiated milk thistle products are standardized to contain 70 to 80 percent silymarin – normally available in doses of 120 to 140 milligrams. Because silymarin and its components do not dissolve well in water, seek complex silymarin-phosphatydalcholine; lipid increases the absorption of silymarin for maximum health benefits.

References:

http://www.ncbi.nlm.nih.gov/pubmed/25617046
http://umm.edu/health/medical/altmed/herb/milk-thistle
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3612568
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098397

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