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Health Ministry issues notification on Japanese Encephalitis (JE)

Delhi: In order to address the issue of Japanese encephalitis in some regions of the country, the Ministry of Health and Family Welfare has issued a notification on Japanese encephalitis, here today. The notification has been sent to the heads of state health departments and other health officials from all State Governments / UT concerned. In addition, Chief Secretaries of Government of Assam, Bihar, Tamil Nadu, Uttar Pradesh and West Bengal, where the number of JE cases reported to be high in the past, have been requested to issue the notification required in the clinical setting (Registration and Regulation) Act 2010 or Act of matter / Rules as applicable, to ensure the necessary monitoring, prevention and control of disease.

During the debate on a motion calling attention in the Lok Sabha 11/08/2016 regarding spread of encephalitis in the country, especially eastern Uttar Pradesh and measures taken by the Government to this regard, the Union Minister of health and Family Welfare, Sri JP Nadda had made a guarantee for the manufacture of Japanese encephalitis (JE) disease notifiable. Circular notice issued today is in response to the aforementioned insurance.

The text of the Notice reads as follows:

  1. Japanese encephalitis (JE) is a major public health problem in the country accounting for high morbidity, mortality and disability. the first reports of EJ is necessary for the effective implementation of prevention and case management.
  1. In order to ensure the management and early diagnosis of cases, reduce transmission, addressing the problems of emergence and spread of diseases in newer geographies is essential to have information full of all cases of EJ. Therefore, the health professionals should report all cases to local authorities JE ie Official District Health / Chief Medical Officer of the district concerned and official Municipal Health Municipal Corporation / Municipality concerned every week (every day during the transmission period).
  1. Therefore, all laboratory-confirmed cases of Japanese encephalitis should be notified as detailed below.
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(A) Definition of a laboratory-confirmed case JE:

patient having any of the following:

  • The presence of IgM specific to the JE virus in a single sample of cerebrospinal fluid (CSF) or serum antibodies, as detected by an IgM capture ELISA specifically for JE virus.
  • Detection of a four-fold increase or greater in specific antibodies JE virus as measured by hemagglutination inhibition (HI) or neutralization assay plaque reduction (PRNT) serum collected during acute and convalescent phase of the disease. The two IgG samples must be collected at least 14 days apart. LgG test should be performed in parallel with other confirmatory tests to eliminate the possibility of cross-reactivity.
  • JE virus isolation in serum, plasma, blood, CSF or tissue. Antigen detection JE virus in tissue by immunohistochemistry;
  • Detection genome JE virus in serum, plasma, blood, CSF or tissue by the reaction of reverse transcriptase polymerase chain (PCR) or test nucleic acid amplification equally sensitive and specific.

(B) A suspect case is defined as:

A person of any age, at any time of year, with the sudden onset of fever, no more than 5-7 days duration and a change in mental status (including symptoms such as confusion, disorientation, coma, or the inability to talk) and / or new onset of seizures (excluding simple febrile seizures). Other early clinical findings may include increased irritability, drowsiness or abnormal behavior greater than that observed with usual febrile illness.

  1. For the purposes of this notice, health care providers include Run-clinical or establishment run by the government (including local authorities), private or NGO sectors and / or individual professionals under Clinical Establishment (Registration and regulation) Act, 2010.
  1. doctors are required in government health agencies and private sector professionals registered hospitals / private clinics to report immediately to the office of the Health Authority District in the district concerned doctors, if a suspected case of JE is reported in its health institution.
  1. Blood samples of suspected cases of JE all have to be sent to Hospital Sentinel surveillance JE (SSH), to be held by ELISA. If so information should be sent to the office of the District Health Authority immediately after diagnosis.
  1. The management of JE cases needs to be done in accordance with the guidelines issued by the Government of India from time to time and available-le on the website of the Directorate of the National Program Control vector (NVBDCP), Government of India transmitted diseases.
  1. For more detailed information, interested State Official Program, NVBDCP whose details are available at www.nvbdcp.gov.in can be contacted.
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