Home » Glioblastoma discovery: Scientists could stop 'devastating' brain tumour from spreading

Glioblastoma discovery: Scientists could stop 'devastating' brain tumour from spreading

Medical researchers believe the new technique could lead to better survival of patients with glioblastoma, which it is one of the most common types of malignant brain tumors in adults.

Little is known about how the tumor is formed and the way it seeps into the brain tissue.

tumor has threadlike tendrils spread to other parts of the brain so it is difficult to remove everything.

The study, led by Dr. Elodie Siney under the supervision of Dr. Sandrine Willaime-Morawek, teacher mother and brain repair cells, University of Southampton.

team analyzed how calls ADAM enzymes affects movement and function of human tumor cells.

findings suggest that if doctors are able to block specific enzymes called ADAM10 and ADAM17, the tumor stops growing and spreading.

as leading to cancer cells away from where they were growing up which could allow them to be removed through traditional cancer treatments such as radiotherapy, chemotherapy or surgery.

Dr. Willaime-Morawek said: “When I confirmed in animal models of glioblastoma, this finding will be important for patients and physicians

.” Glioblastoma is a devastating disease that is often untreatable


We found that blocking ADAM can lead to a reduced and less recurrence after conventional treatments tumor growth, improved the possibilities of full and improve survival rates “surgical removal.

glioblastoma (or GBM for short) belongs to a group of brain tumors known as gliomas.

This means that grows from a type of brain cells called glial cells.

is the most common primary tumor brain in adults and is also the most aggressive form of brain tumor. the glioblastomas are considered grade 4, as they are fast and has a propensity to spread

the study was published in Molecular Neurobiology

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