body’s natural defenses could be exploited in a possible new treatment for eczema, scientists have found.
A British study published in the Journal of Investigative Dermatology, has discovered a way to instruct the skin cells to produce protective substances people with eczema often lack.
Researchers hope the discovery will help prevent or create new treatments for atopic eczema.
also called atopic dermatitis, the condition causes itchy lesions distressing that can lead to broken skin with increased susceptibility to infection.
can have a severe impact on people’s lives, work and sleep.
Conventional treatment with steroid creams can have side effects and become less effective over time, a natural therapy that could prevent.
suffer from eczema are at increased risk of carrying the bacteria known as Staphylococcus aureus on the skin, which can infect skin lesions and damage the skin barrier.
also typically produce a protective compound not naturally occurring in the cells of human skin defensins known as beta 2 (hBD2).
The researchers found that the compound is of vital importance in preventing damage to the barrier of the skin caused by Staphylococcus aureus.
hBD2 found that when applied to skin cells grown in the laboratory, which helped keep the skin intact, with cells that strengthen the protection against damage caused by bacteria such as the mortar between the bricks.
Dr. Donald J Davidson, a researcher at the University of Edinburgh MRC Centre for research of inflammation, who led the study, said: “This is a great opportunity to work with something that the body produces naturally to develop new therapies for atopic eczema, which affects the lives of many people. ”
Study: University of Edinburgh MRC Centre for research of inflammation
Principal investigator: Dr. Donald J Davidson, Rresearch Fellow at the University of Edinburgh
study published by: Journal of Investigative Dermatology