The Western medical system is finally beginning to face the fact that the marijuana is not a drug.? is a drug
more than 5000 years of use throughout many cultures and hundreds of different studies have demonstrated the safety and efficacy of cannabis, so what more is expected of
An accelerated cannabinoids [course
cannabis contains compounds called cannabinoids, which stimulate
endocannabinoid system. This system is composed of lipids and neuromodulators located in the brain (particularly in the cerebellum, cerebral cortex, hippocampus, basal ganglia and spinal cord) and throughout the central nervous system and peripheral cannabinoid receptors. These receptors are also found in various organs, connective tissues, glands and immune cells ( 1 ).
Because the endocannabinoid system is connected to many different systems and brain, often described as a bridge between the body and the mind
There are two classes of two cannabinoid receptors ( 2 ) :.
CB1 are mostly present in the nervous system, connective tissues, gonads, glands and organs. They mediate physiological effects on the central nervous system and has been reported to modulate immune responses.
CB2 are found predominantly in the immune system and its associated structures. They are known to inhibit inflammation and edema, reduce pain and protect the liver from injury. In addition, researchers believe that these receptors may be the key to the treatment of atherosclerosis and osteoporosis.
Most body tissues contain both CB1 and CB2 receptors, which work together to perform different actions. Researchers believe that there is a third cannabinoid receptor, but it remains to be discovered. These receptors are also thought to outnumber any other receptor system.
body, even produces its own cannabinoids in endothelial cells, adipocytes, glial cells, macrophages, and Purkinje cells ( 3 ). They are produced by neurons “a la carte” to alter the way the information is received and filtered in order to create a calming ( 4 ) effect.
Psychologically, the substances promote a state of more social and positive mood, promoting exchange, humor and creativity. Also affect learning and plasticity for a person more open minded and more likely to go beyond regular thought patterns.
Cannabis is the most widely known and well studied phytocannabinoids (plant-derived cannabinoids) containing 65 similar cannabinoid substances source. Of the 65, only the Δ9-tetrahydrocannabinol (THC), Δ8-tetrahydrocannabinol and cannabidiol are known to activate both CB1 and CB2 ( 5 6 ).
however, other plants produce cannabinoids and cannabinoid-like substances that may be similar to those of marijuana beneficial properties.
much remains unknown about the compounds that trigger endocannabinoid- and the endocannabinoid system in general, but here are 6 plants have expanded our these substances and structures.
cannabinoids Herbal Other
Here are some more ways that encourage legal notice to the endocannabinoid system!
1. Echinacea ( Echinacea)
Echinacea is mainly used to combat the common cold, but it is also beneficial in the treatment of indigestion, ADHD syndrome chronic fatigue, migraines, chronic pain, and urinary tract infections ( 6 ). The plant even made it in the US National Formulary from 1916 to 1950, until you feel forgotten in favor of antibiotics ( 7 ).
Echinacea does not contain the same type of cananbinoids as cannabis, but contains N-alkylamides (alkamides), which CB2 receptors bind to regulate the immune system, minimize pain and reduce inflammation ( 8 ).
2. Electric Daisy ( oleracea Acmella )
In its native Amazon, electric daisy is used to treat toothaches, ulcers, irritable bowel syndrome, abscesses, and to clean between the teeth ( 9 ). His most prized distinction, however, is its remarkable analgesic properties, since blocking nerve numbness to provide for more than an hour without any side effects ( 10 ) terminations.
The compound cannabinoid-as responsible for this is called N-isobutylamides. Like echinacea, electric daisy binds to CB2 receptors.
3. Woolly umbrella Helichrysum ( Helichrysum umbraculigerum )
This daisy South Africa has two mood stabilizers and antidepressant effects thanks to its cannabigerol content. For a 2014 International Society for Research on Cannabinoids meeting, chemical Italian natural product Giovanni Appendino explained that this substance is the precursor of the active cannabinoids in cannabis, THC, CBD, and CBC (cannabichromene). As with cannabis, the plant is burned during sacred ceremonies and fumes to create a psychotropic effect ( 11 12 ).
Woolly umbrella Helichrysum has great potential in the world of natural medicine, but it is difficult to study because the laws bio-piracy of South Africa prohibit the collection and export of native species or seeds to prevent exploitation foreign. Fortunately, Helichrysum cannabinoids are also found in liver
4. Liver (Radula marginata)
Just as cannabigerol, this native New Zealand contains a bibenzyl-cannabinoid type compound freshly discovered called perrottetinenic acid. Unlike most of cannabinoid compounds, perrottetinenic acid binds to the CB1 receptor ( 13 ).
Liverwort also contains two previously unknown bibenzyls and a known cannabinoid perrottetinene. This large number of compounds may explain their ability to treat bronchitis and heal the gallbladder, liver and bladder problems.
5. Cacao ( Theobroma cacao )
is no secret that chocolate improves mood, but scientists are just beginning to discover how this food really it works. It contains N-linoleoylethanolamide and N-oleoylethanolamide, which prevents the breakdown of the endocannabinoid anandamide down by deactivating the enzyme FAAH. Anandamide is released by neurons and binds to the cannabinoid receptors with high affinity and mimics the effects of cannabinoid drugs. This increases their senses and improves the well, which may explain why we experience chocolate cravings ( 14 ).
Chocolate can also contain lipids chemically related to anandamide. Study found that the food contains three main compounds, but N-acylethanolamine remains understood
6. Black Pepper ( Piper nigrum)
has a lot more black pepper to offer than just a flavor boost. Β-caryophyllene contains, a cannabinoid that binds to CB2 receptors to reduce inflammation. It is also a common scent molecule found in many essential oils ( 15 ).
β-caryophyllene is easily digestible and can be beneficial in the treatment of arthritis and osteoporosis.