About 90% of patients diagnosed with cervical cancer have local symptoms. Systemic symptoms are not as common.
local manifestation of the disease
early stages of the disease can be asymptomatic, ie, without any symptoms. The first symptoms that indicate a more or less advanced stage include:
1. The leg pain
In the early stages of cervical cancer, some women experience leg pain and swelling. In the second case, neck swollen uterus can lead to a blockage of blood flow, which then leads to swelling of the legs and pain, pain sensation.
2. hard Urination
The presence of cervical cancer can be revealed by the newspaper urination analysis. In most cases, if it comes to urinary symptoms, the cancer has spread to nearby tissues and requires immediate attention.
discomfort when urinating is the most obvious symptom immediately and frequent. Typically, these symptoms are connected to a tight feeling and concentrate stinging, but can take several different hard sensations.
3. Dirty, yellowish (sometimes even blood)
4. Bleeding after intercourse
As the tumor grows and spreads in the cervix, bleeding becomes heavier, irregular, accompanied by pain in the pelvis, spine and legs. Sometimes the patient has swelling in the lower extremities due to metastatic lymph nodes compress blood vessels.
If the tumor develops in all tissues and organs, symptoms correspond to the affected organ.
For example, when the tumor affects the patient’s bladder causes: frequent urination, burning sensation, and blood in the urine (hematuria)
When it affects the rectum, which develops symptoms such as urgency, painful defecation, blood in stool (melena). When compressed infiltrates or ureter (upper urinary tract), which causes hydronephrosis and renal failure or insufficiency.
In more advanced disease, which can lead to the development of rectovaginal fistula and vesicovaginal stages.
Systemic symptoms and signs are less frequent compared to the local. hematogenous spread is rare, especially during the diagnostic stage of the disease. This is why symptoms and signs of distant metastases rarely occur during the diagnostic phase of the disease.
However, in advanced stages of the disease, the tumor can spread through the blood to other tissues and organs. It can affect any organ and tissue. However, cancer metastasis often affect cervix, lung, liver, brain and bones.
If there are metastases in the body, certain clinical symptoms and signs of organ or tissue is affected. Therefore, in cases of bone metastases, the patient feels pain in the bones, and there is a possibly pathological fractures of affected bone.
If pulmonary metastases, the patient will have respiratory problems such as cough, dyspnea, hemoptysis and. Lung metastases are not so common.
If the tumor affects the liver, the patient feels tenderness below the (enlarged liver palpable) the right costal arch and hepatomegaly. Metastasis extensive covering a large part of the liver disorders cause many metabolic functions in the body, jaundice, weakness, malaise, and even coma.
metastases in the brain cause neurological symptoms such as headaches, vomiting, double vision, impaired balance.
regional metastases develop swelling in the legs (in the presence of metastatic lymph nodes packages groin) lymph nodes. Metastases in the para-aortic lymph nodes cause pain, especially in the lower back and back, and occurs as a result of compression of enlarged lymph nodes in the nerves.
Common symptoms of an advanced stage include: general weakness, fatigue, loss of appetite, anemia, uremia and secondary infections
The paraneoplastic syndrome
In rare cases, cervical cancer can cause a paraneoplastic syndrome as a unique manifestation of the disease. It can develop:
- hypercalcemia (high calcium levels in the blood)
- values inadequate ACTH (adrenocorticotropic hormone that stimulates the adrenal cortex to produce glucocorticoids such as cortisol)
- values inadequate ADH (antidiuretic hormone that increases water reabsorption in the distal tubule of the kidney).